Traveling with a portable oxygen concentrator takes a little preparation, but once you know the rules and have the right bag, it's straightforward. This checklist covers everything from FAA approval to what TSA actually needs from you at security.
Confirming Your Device Is FAA-Approved
Most modern units — including Inogen One G3, G5, Rove 6, OxyGo Next, and Rhythm P2 — are FAA-approved for in-cabin use. Check your device's user manual for the FAA approval label, then call your airline at least 48 hours before your flight to notify them and confirm their specific requirements. Airlines are required by the Air Carrier Access Act to allow FAA-approved concentrators, but advance notice is always required.
Packing Extra Batteries the Right Way
The FAA requires you to carry at least 1.5 times the battery life needed for your total flight time, including layovers. All batteries must travel in the cabin — not in checked luggage.
A backpack with a dedicated zippered battery compartment keeps spares organized and reachable without unpacking everything else. Our OxyGo Next backpacks are built with a zippered bottom compartment that fits both single and double batteries — you can swap mid-flight without removing the device from the bag. Prices start at $54.99 with free US shipping on orders over $54.99.
Keeping Your Device Accessible at Security
TSA treats portable oxygen concentrators as medical devices. You will be asked to remove it from its bag and place it in a tray separately — similar to a laptop. Inform the TSA officer immediately that you have a medical oxygen device so they can direct you to the right screening lane.
A bag that opens quickly without disturbing everything else saves significant time here. Our OxyGo Next backpacks open via a top zipper and zippered bottom panel so the device is out in seconds.
Cannula and Tubing Storage for Travel
Tangled tubing is one of the most common frustrations in transit, especially in tight airplane seating. A bag with a built-in cannula channel routes the tubing cleanly from the device compartment to the outside without kinking. Keep a spare cannula in an outer pocket — airplane air is dry and extended wear can cause irritation.
Documentation Worth Bringing Along
Carry these in an outer pocket so they're immediately accessible if airline staff or TSA have questions:
- A physician's letter stating your diagnosis, prescribed flow rate, and that you require oxygen during flight
- Your device's FAA approval documentation
- Your device's user manual
- Your airline's confirmation number if they gave you one when you called ahead
Frequently Asked Questions
Do all airlines allow portable oxygen concentrators?
Most major US airlines do for FAA-approved devices under the Air Carrier Access Act. Always call ahead with your specific device model — at least 48 hours before your flight.
How many batteries should I travel with?
Calculate your total flight time including layovers, then multiply by 1.5. That is your minimum battery hours. Check your device manual for battery runtime per flow setting — higher flow rates reduce battery life.
Can I use my concentrator during the flight?
Yes, for FAA-approved devices you can use your concentrator throughout the entire flight including takeoff and landing. This is one of the key advantages over oxygen tanks, which are not permitted on commercial flights.
Does O2TOTES make travel bags for oxygen concentrators?
Yes — O2TOTES has been making device-specific oxygen concentrator backpacks since 2007. Every bag is built around your exact device model with features designed for travel: zippered battery access, cannula holder, quick-open design for TSA, and breathable mesh ventilation. Our OxyGo Next backpacks start at $54.99. We also carry purpose-built bags for Inogen G3, Inogen G5, Inogen Rove 6, Rhythm P2, and Caire Freestyle Comfort.
Get travel-ready — shop OxyGo Next backpacks built for life on the go. Free US shipping on orders over $54.99.














